KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
44.85
Human Site:
S590
Identified Species:
65.78
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
S590
D
E
E
E
L
F
H
S
I
R
M
D
N
P
F
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
S590
D
E
E
E
L
F
H
S
I
R
M
D
N
P
F
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
S1023
D
E
D
E
L
F
E
S
I
R
V
D
T
P
H
Dog
Lupus familis
XP_849292
706
81555
S590
D
E
E
E
L
F
H
S
I
R
M
D
N
P
F
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
S590
D
E
E
E
L
F
H
S
I
R
M
D
N
P
F
Rat
Rattus norvegicus
Q9WTQ0
707
81732
S590
D
E
E
E
L
F
H
S
I
R
M
D
N
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
S592
D
E
E
E
L
F
H
S
I
R
M
D
N
P
F
Chicken
Gallus gallus
NP_001006133
699
80179
S582
D
E
D
E
L
F
E
S
I
R
V
D
T
P
H
Frog
Xenopus laevis
Q7LZQ8
671
76506
S549
D
E
D
E
L
F
Q
S
I
M
E
H
N
V
A
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
S549
D
E
D
E
L
F
Q
S
I
M
E
H
H
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
S513
N
E
D
E
L
F
D
S
I
M
H
D
D
V
L
Honey Bee
Apis mellifera
XP_394743
624
71014
S512
D
E
D
E
L
F
W
S
I
C
N
E
R
P
F
Nematode Worm
Caenorhab. elegans
P34722
704
80280
S586
G
E
D
E
L
F
D
S
I
L
N
E
R
P
Y
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
H512
V
K
G
D
V
R
A
H
Q
F
F
K
S
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
A1035
D
E
D
E
V
F
N
A
I
L
T
D
E
P
L
Red Bread Mold
Neurospora crassa
P87253
1142
127954
A1028
D
E
D
E
I
Y
D
A
I
L
A
D
E
P
L
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
66.6
100
N.A.
100
100
N.A.
100
66.6
53.3
46.6
N.A.
46.6
60
46.6
0
P-Site Similarity:
100
100
80
100
N.A.
100
100
N.A.
100
80
60
60
N.A.
66.6
73.3
66.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
13
0
0
7
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
82
0
57
7
0
0
19
0
0
0
0
69
7
0
7
% D
% Glu:
0
94
38
94
0
0
13
0
0
0
13
13
13
0
0
% E
% Phe:
0
0
0
0
0
88
0
0
0
7
7
0
0
0
44
% F
% Gly:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
38
7
0
0
7
13
7
0
13
% H
% Ile:
0
0
0
0
7
0
0
0
94
0
0
0
0
7
0
% I
% Lys:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% K
% Leu:
0
0
0
0
82
0
0
0
0
19
0
0
0
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
19
38
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
7
0
0
0
13
0
44
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
75
0
% P
% Gln:
0
0
0
0
0
0
13
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
7
0
0
0
50
0
0
13
0
0
% R
% Ser:
0
0
0
0
0
0
0
82
0
0
0
0
7
0
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
7
0
13
0
0
% T
% Val:
7
0
0
0
13
0
0
0
0
0
13
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _